What is exercise index?
Physical activity is one of the most widely studied habits in healthy aging. Movement strengthens the heart and lungs, builds and maintains muscle, supports bone, helps the body handle blood sugar and can lift mood. The benefits come from a range of activity types, from brisk walking to strength training to sport. The exercise index looks at how your overall activity pattern may be reflected in your biology, rather than counting steps or workouts.
How your genes play a role
Exercise influences DNA methylation in muscle, blood and other tissues. Studies have found that people who are regularly active tend to show methylation patterns that differ from less active people, including in genes tied to metabolism and muscle function. Research has also linked regular activity with a younger epigenetic age. The index combines relevant methylation markers to estimate how your activity may be shaping your biological aging.
Many people move regularly but are unsure whether it is making a meaningful difference. This index offers a biological perspective on that effort. It can be encouraging to see activity reflected in your results, and helpful to notice if there is room to do more or to vary what you do. Paired with your clinician's guidance, it can support choices that fit your body, schedule and goals.
What your report shows
Your Exercise Index results are explained in plain language in your private EvoDNA account, alongside the other areas in your kit.
- Activity signatureAn estimate of how your physical activity is reflected in your methylation patterns.
- Link to biological ageHow your activity profile may relate to your overall epigenetic age.
- Metabolic contextSignals connected to how movement may support your energy and blood sugar systems.
- Progress over timeWith repeat testing, how your index responds as your routine evolves.
Each result comes with a plain-language explanation and practical points to discuss with your clinician.
Illustration only. Your report reflects your own genetic results.
Putting results to use
Many people use their results as a starting point for conversations with their clinician about:
Regular walking is one of the simplest and most widely recommended forms of activity.
Resistance exercise a few times a week is often suggested to maintain muscle and bone.
Standing or moving briefly during long periods of sitting is commonly encouraged.
Rest days and good sleep help your body adapt to the activity you do.
Questions
Does the type of exercise matter?
Research suggests both aerobic and strength activity have benefits. A varied routine that you enjoy and can sustain is often the most practical approach.
I am very active. Will this confirm it?
Active people often show methylation patterns associated with activity. Your results can show how your routine appears at the cellular level, which may or may not match your expectations.
Is it too late to start?
Research suggests the body responds to activity at every stage of life. Your clinician can help you choose a safe and comfortable starting point.
