What is thyroid health?
The thyroid is a butterfly shaped gland that makes hormones controlling metabolism, the speed at which your body uses energy. These hormones influence heart rate, body temperature, digestion, energy, skin, hair and mood. The system is guided by the brain, which releases TSH to tell the thyroid when to produce more. Thyroid hormone is made using iodine from your diet and then converted into its active form in tissues throughout the body.
How your genes play a role
Genes influence the development of the thyroid gland, the enzymes that build its hormones and the receptor that receives TSH. Others relate to the immune system and are linked to how likely it may be to mistakenly target the thyroid, which is the basis of the most common thyroid conditions. Variants also affect how efficiently the body converts thyroid hormone into its active form.
Thyroid changes can be gradual and easy to dismiss as stress or tiredness. Understanding your genetic context may help you notice patterns sooner and ask more informed questions. It can be especially helpful if thyroid conditions run in your family. Combined with routine blood tests and a conversation with your clinician, it gives a fuller picture of this quiet but central gland.
What your report shows
Your Thyroid Health results are explained in plain language in your private EvoDNA account, alongside the other areas in your kit.
- Hormone productionVariants in genes that build thyroid hormone inside the gland.
- TSH signalingHow your TSH receptor gene may influence the thyroid's response to the brain.
- Immune tendencyImmune related variants linked to autoimmune thyroid patterns.
- Gland developmentGenes that guide how the thyroid forms and functions.
| Gene | What it does | Result |
|---|---|---|
| TPO | Makes thyroid peroxidase, the enzyme that attaches iodine to… | Typical |
| TG | Makes thyroglobulin, the protein framework on which thyroid hormone… | Moderate effect |
| TSHR | Codes for the receptor that receives TSH, the brain's… | Typical |
Each result comes with a plain-language explanation and practical points to discuss with your clinician.
Illustration only. Your report reflects your own genetic results.
Genes we analyze
| Gene | Role |
|---|---|
| TPO | Makes thyroid peroxidase, the enzyme that attaches iodine to build thyroid hormone. |
| TG | Makes thyroglobulin, the protein framework on which thyroid hormone is assembled. |
| TSHR | Codes for the receptor that receives TSH, the brain's signal to make more thyroid hormone. |
| FOXE1 | A gene that helps direct how the thyroid gland develops and functions. |
| PAX8 | Guides thyroid development and helps switch on genes needed for hormone production. |
Full panel: 13 genes
TPO, TGAB, TSH, TSHR, TG, DEIODINASE, PRNP, HLA-DRB1, HLA-DQ2, HLA-DQ8, FOXE1, PAX8, TITF1
Putting results to use
Many people use their results as a starting point for conversations with their clinician about:
Iodine is essential for thyroid hormone, and both too little and too much are worth discussing with a clinician.
Selenium supports thyroid enzymes, and foods such as fish and eggs are common sources.
Simple blood tests can track thyroid function, especially if it runs in your family.
Steady sleep and stress care support the brain signals that guide your thyroid.
Questions
Can my DNA tell me if my thyroid is working well?
No. A blood test is needed to measure current thyroid function. Your genes add context about tendencies, such as immune patterns or hormone production.
Do thyroid conditions run in families?
They often do, particularly autoimmune thyroid conditions. Your results can add to what you know about your family history.
What should I do with my results?
Share them with your clinician, who can decide whether any thyroid testing or follow up would be helpful for you.
Only interested in this area? The Thyroid & Metabolism Genetic Report is available on its own for $99.00.
