Brain & Mood

Mental Health

Understanding the biology that shapes your resilience

Mental health is shaped by your story, your surroundings and your biology all at once. Learning about the biological part can make the whole picture feel a little clearer and a little kinder.

  • 13 genes analyzed
  • At-home saliva test
  • Results in 3–4 weeks

What is mental health?

Mental health describes how you think, feel and cope with daily life. It covers emotional balance, the ability to handle stress, and the capacity to connect with others and find meaning. It is not a fixed state. It moves with seasons of life, health, sleep and circumstance. Brain chemistry, hormones, relationships and life experiences all interact to shape how you feel and function from day to day.

How your genes play a role

Research suggests that many genes each contribute a small amount to mental health tendencies. Some influence serotonin signaling, others shape the stress hormone system or the way brain cells communicate through calcium channels. Importantly, genes interact with experience. The same variant may matter more or less depending on stress, support and lifestyle, which is why genes never tell the whole story.

Knowing your biological tendencies can help replace self blame with understanding. If your stress system may be more reactive, or your serotonin signaling may differ from average, it can make sense to prioritize the routines that steady you. Many people find this knowledge useful when talking with a therapist, physician or psychiatrist about their care. It is one thoughtful input among many, never a label.

What your report shows

Your Mental Health results are explained in plain language in your private EvoDNA account, alongside the other areas in your kit.

  • Serotonin signalingHow your serotonin transporter and receptor genes may differ from the average.
  • Stress resilienceVariants linked to how your body regulates and recovers from stress hormones.
  • Neural connectionHow your genes may influence the growth and flexibility of brain connections.
  • Signaling channelsVariants in calcium channels that help brain cells communicate.
Sample reportBrain & Mood
Mental Health13 genes analyzed
GeneWhat it doesResult
SLC6A4Codes for the serotonin transporter, which recycles serotonin after…Typical
5HTR2AMakes a serotonin receptor involved in mood, perception and…Moderate effect
FKBP5Helps fine tune the body's response to cortisol and…Typical
What this means for you

Each result comes with a plain-language explanation and practical points to discuss with your clinician.

Illustration only. Your report reflects your own genetic results.

Genes we analyze

GeneRole
SLC6A4Codes for the serotonin transporter, which recycles serotonin after it has carried a signal.
5HTR2AMakes a serotonin receptor involved in mood, perception and how the brain processes information.
FKBP5Helps fine tune the body's response to cortisol and is widely studied in stress research.
BDNFProduces a growth factor that supports the health and adaptability of brain cells.
CACNA1CCodes for a calcium channel that helps regulate signaling between brain cells.
Full panel: 13 genes

SLC6A4, COMT, BDNF, FKBP5, 5HTR1A, 5HTR1B, 5HTR2A, HTR1A, CACNA1C, CRH, CRHR1, DISC1, NRG1

Putting results to use

Many people use their results as a starting point for conversations with their clinician about:

Sleep routine

Consistent, sufficient sleep is often one of the first topics clinicians explore for emotional wellbeing.

Gentle movement

Regular physical activity is widely associated with better mood and stress handling.

Supportive ties

Staying connected with trusted people may help buffer difficult periods.

Professional support

Talking with a therapist or physician can help you turn insight into a plan that fits you.

Questions

Can a DNA test diagnose a mental health condition?

No. Genetic results cannot diagnose any condition. Diagnosis requires a qualified professional who considers your history, symptoms and circumstances.

If I carry a variant, will I struggle?

Not necessarily. Most variants have small effects and interact with your environment and experiences, so many people with them never face related challenges.

Who should I share my results with?

Your physician, psychiatrist or therapist can help you interpret your results in context. If you are struggling right now, please reach out to a professional or a local support line.

Only interested in this area? The Mood & Emotions Genetic Report is available on its own for $99.00.

Evo Blueprint

Evo Blueprint

Read your Mental Health genes, and 47 more areas

  • One painless saliva sample, collected at home
  • Clear, plain-language report for every area
  • Private and secure. Your data is never sold
  • Results in your EvoDNA account in 3–4 weeks

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This content is for educational purposes and is not medical advice. Genetic results describe tendencies, not diagnoses. Talk with a qualified healthcare professional before making changes to your health care.