What is inflammation?
Inflammation is a protective response. When tissue is injured or under threat, immune cells release messenger proteins that increase blood flow, draw in helper cells and begin repair. The familiar signs are warmth, redness and swelling. In a healthy pattern, this response rises when needed and then settles. When it lingers at a low level over long periods, research suggests it may be linked to many aspects of aging and wellbeing.
How your genes play a role
Your genes help set the volume. Cytokine genes such as IL6, IL1B and TNF influence how strongly the alarm sounds, while IL10 and TGFB1 help calm it down. Other genes, including SOD2, GSTM1 and GSTT1, relate to how your body handles oxidative stress and processes certain compounds, which can feed into the inflammatory picture.
Knowing your inflammatory tendencies can help you notice patterns in your own life, such as how you recover after exercise, travel or a poor night of sleep. It can make lifestyle choices feel more personal and less generic. Many people find it a useful lens for conversations with their clinician about food, movement, rest and stress, all of which are closely tied to how the body manages inflammation.
What your report shows
Your Inflammation results are explained in plain language in your private EvoDNA account, alongside the other areas in your kit.
- Your alarm signalsVariants in genes that may influence how strongly your body starts an inflammatory response.
- Your calming signalsGenes linked to how efficiently your body may resolve inflammation afterward.
- Oxidative balanceAntioxidant and detoxification genes that relate to how your cells manage everyday stress.
- Recovery tendenciesA picture of how your genetic profile may relate to bouncing back after physical strain.
| Gene | What it does | Result |
|---|---|---|
| IL6 | Produces a messenger protein that helps start and coordinate… | Typical |
| CRP | Makes C-reactive protein, a protein the liver releases during… | Moderate effect |
| IL10 | Produces an anti-inflammatory messenger that helps bring an immune… | Typical |
Each result comes with a plain-language explanation and practical points to discuss with your clinician.
Illustration only. Your report reflects your own genetic results.
Genes we analyze
| Gene | Role |
|---|---|
| IL6 | Produces a messenger protein that helps start and coordinate inflammation, and also has roles in metabolism. |
| CRP | Makes C-reactive protein, a protein the liver releases during inflammation and a common marker in blood tests. |
| IL10 | Produces an anti-inflammatory messenger that helps bring an immune response back to rest. |
| SOD2 | Makes an antioxidant enzyme inside mitochondria that helps neutralize reactive oxygen molecules. |
| GSTM1 | Encodes an enzyme that helps the body process and clear certain environmental compounds. |
Full panel: 15 genes
IL6, IL1B, TNF, CRP, IL10, IL4, IL13, TGFB1, NF-KB, NOS2, COX2, CYP2E1, GSTM1, GSTT1, SOD2
Putting results to use
Many people use their results as a starting point for conversations with their clinician about:
Diets rich in vegetables, fruit, whole grains and healthy fats are often discussed in the context of inflammation.
Regular, moderate exercise is linked to a healthier inflammatory balance over time.
Consistent sleep gives the body time for repair and is closely tied to inflammatory signaling.
Practices such as time outdoors, breathing exercises or meditation may help support a calmer baseline.
Questions
Is inflammation bad?
Not at all. Short-term inflammation is essential for healing and defense. Interest tends to focus on whether it resolves well or lingers at a low level over time.
Can my genes tell me my current inflammation level?
No. Genes describe tendencies, while your current level depends on recent activity, diet, sleep and health. Blood markers such as CRP, ordered by a clinician, measure what is happening now.
What does oxidative stress have to do with inflammation?
Oxidative stress happens when reactive molecules outpace the body's antioxidant defenses. The two processes can reinforce each other, which is why antioxidant genes are included in this area.
Only interested in this area? The Everyday Inflammation Genetic Report is available on its own for $99.00.
